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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
19.39
Human Site:
S334
Identified Species:
35.56
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S334
D
Q
L
D
A
I
S
S
L
P
T
P
S
D
I
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
T199
D
F
L
Y
A
Y
S
T
A
P
G
Y
Y
S
W
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S334
D
Q
L
D
A
V
S
S
L
P
T
P
S
D
I
Dog
Lupus familis
XP_865164
414
45235
S333
D
Q
L
D
A
V
S
S
L
P
T
P
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
R357
K
E
E
L
M
K
M
R
L
P
T
R
S
D
M
Rat
Rattus norvegicus
P55215
452
50709
R357
K
E
E
L
M
K
M
R
L
P
T
R
S
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
S284
D
E
P
D
A
V
A
S
L
P
T
P
S
D
I
Chicken
Gallus gallus
Q98943
424
47941
R328
K
E
E
N
L
K
L
R
L
P
T
R
S
D
M
Frog
Xenopus laevis
P55866
282
32106
F204
R
I
P
V
E
A
D
F
L
Y
A
Y
S
T
V
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
S349
D
E
L
D
A
R
A
S
L
P
T
P
S
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
N245
P
G
Y
F
S
W
R
N
I
N
N
G
S
W
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
K408
Q
V
Q
Q
V
W
R
K
K
P
S
Q
A
D
I
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
K348
S
F
A
S
S
R
S
K
V
P
S
Q
S
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
33.3
93.3
93.3
N.A.
33.3
33.3
N.A.
73.3
33.3
13.3
80
N.A.
6.6
N.A.
20
26.6
P-Site Similarity:
100
40
100
100
N.A.
46.6
46.6
N.A.
93.3
53.3
20
93.3
N.A.
26.6
N.A.
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
47
8
16
0
8
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
39
0
0
8
0
0
0
0
0
0
77
0
% D
% Glu:
0
39
24
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
16
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
47
% I
% Lys:
24
0
0
0
0
24
0
16
8
0
0
0
0
0
0
% K
% Leu:
0
0
39
16
8
0
8
0
70
0
0
0
0
0
0
% L
% Met:
0
0
0
0
16
0
16
0
0
0
0
0
0
0
31
% M
% Asn:
0
0
0
8
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
8
0
16
0
0
0
0
0
0
85
0
39
0
0
0
% P
% Gln:
8
24
8
8
0
0
0
0
0
0
0
16
0
0
0
% Q
% Arg:
8
0
0
0
0
16
16
24
0
0
0
24
0
0
0
% R
% Ser:
8
0
0
8
16
0
39
39
0
0
16
0
85
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
62
0
0
8
0
% T
% Val:
0
8
0
8
8
24
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
8
8
0
8
0
0
0
8
0
16
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _